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Isradipine, Tocris Bioscience™

Catalog No. p-4784046 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

CaV1.x blocker

Potent and selective L-type voltage-gated Ca2+ channel blocker. EC50 and pA2 values are 1.4 nM and 10.3 for relaxation of depolarization- and Ca2+-induced contractions of rabbit aorta respectively; EC25 = 0.45 nM for reduction in rate of spontaneously beating guinea pig right atria. Long-acting antihypertensive agent in vivo, exerting primary effects on vascular tissue with secondary negative chronotropic action.

Chemical Identifiers

CAS 75695-93-1
Molecular Formula C19H21N3O5
Molecular Weight (g/mol) 371.39
MDL Number MFCD00153820
InChI Key HMJIYCCIJYRONP-UHFFFAOYNA-N
Synonym isradipine, dynacirc, isradipin, lomir, isrodipine, prescal, dynacirc cr, esradin, clivoten, dynacrine
PubChem CID 3784
IUPAC Name 3-methyl 5-propan-2-yl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
SMILES COC(=O)C1=C(C)NC(C)=C(C1C1=CC=CC2=NON=C12)C(=O)OC(C)C

Specifications

Quantity 10 mg
Formula Weight 371.39
Percent Purity >99%
Chemical Name or Material Isradipine

Safety and Handling

Recommended Storage Store at Room Temperature
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