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JHW 007 hydrochloride, Tocris Bioscience™

Catalog No. 435150 Shop All R&D Systems Products
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High affinity dopamine uptake inhibitor

Dopamine uptake inhibitor; displays high affinity for the dopamine transporter (DAT) (Ki = 25 nM compared to 1330 and 1730 for NET and SERT respectively). Suppresses the effects of cocaine administration in a dose-dependent manner and decreases cocaine and methamphetamine self-administration in rats.

Chemical Identifiers

CAS

202645-74-7

Molecular Formula

C24H30ClF2NO

Molecular Weight (g/mol)

421.957

InChI Key

RHYMGBAYGRUKNZ-DHWZJIOFSA-N

Synonym

jhw 007 hydrochloride, 3-endo-3-bis 4-fluorophenyl methoxy-8-butyl-8-azabicyclo 3.2.1 octane hydrochloride

PubChem CID

71771746

IUPAC Name

(1S,5R)-3-[bis(4-fluorophenyl)methoxy]-8-butyl-8-azabicyclo[3.2.1]octane;hydrochloride

SMILES

CCCCN1C2CCC1CC(C2)OC(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F.Cl

Specifications

Quantity

50 mg

Formula Weight

421.95

Percent Purity

>99%

Chemical Name or Material

JHW 007 hydrochloride

Recommended Storage

Store at -20°C
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