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  8. JHW 007 hydrochloride, Tocris Bioscience™

JHW 007 hydrochloride, Tocris Bioscience™

Catalog No. p-4816580 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

High affinity dopamine uptake inhibitor

Dopamine uptake inhibitor; displays high affinity for the dopamine transporter (DAT) (Ki = 25 nM compared to 1330 and 1730 for NET and SERT respectively). Suppresses the effects of cocaine administration in a dose-dependent manner and decreases cocaine and methamphetamine self-administration in rats.

Chemical Identifiers

CAS 202645-74-7
Molecular Formula C24H30ClF2NO
Molecular Weight (g/mol) 421.957
InChI Key RHYMGBAYGRUKNZ-DHWZJIOFSA-N
Synonym jhw 007 hydrochloride, 3-endo-3-bis 4-fluorophenyl methoxy-8-butyl-8-azabicyclo 3.2.1 octane hydrochloride
PubChem CID 71771746
IUPAC Name (1S,5R)-3-[bis(4-fluorophenyl)methoxy]-8-butyl-8-azabicyclo[3.2.1]octane;hydrochloride
SMILES CCCCN1C2CCC1CC(C2)OC(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F.Cl

Specifications

Quantity 10 mg
Formula Weight 421.95
Percent Purity >99%
Chemical Name or Material JHW 007 hydrochloride

Safety and Handling

Recommended Storage Store at -20°C
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