Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Benzenoids
  6. Benzene and substituted derivatives
  7. N-phenylureas
  8. JNJ 10397049, Tocris Bioscience™

JNJ 10397049, Tocris Bioscience™

Catalog No. p-4816951 Shop All R&D Systems Products
Click to view available options
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective OX2 receptor antagonist

Selective OX2 receptor antagonist (pIC50 = 7.4 for chimeric OX2 receptors; pKB values are 5.9 and 8.5 for OX1 and OX2 receptors respectively). Shows no significant activity in a panel of over 50 other neurotransmitters and neuropeptide receptors. Achieves high level of OX2 receptor occupancy in the rat brain; exhibits sleep-promoting effects in rats.

Chemical Identifiers

CAS 708275-58-5
Molecular Formula C19H20Br2N2O3
Molecular Weight (g/mol) 484.188
InChI Key RBKIJGLHFFQHBE-IRXDYDNUSA-N
Synonym unii-1b419p24av, n-2,4-dibromophenyl-n'-4s,5s-2,2-dimethyl-4-phenyl-1,3-dioxan-5-yl-urea, 1-2,4-dibromophenyl-3-4s,5s-2,2-dimethyl-4-phenyl-1,3-dioxan-5-yl urea, d01sul, compound 9 pmid: 15261275, 1-2,4-dibromophenyl-3-4s,5s-2,2-dimethyl-4-phenyl-1,3 dioxan-5-yl urea, urea, n-2,4-dibromophenyl-n'-4s,5s-2,2-dimethyl-4-phenyl-1,3-dioxan-5-yl, 3-2,4-dibromophenyl-1-4s,5s-2,2-dimethyl-4-phenyl-1,3-dioxan-5-yl urea
PubChem CID 9869934
IUPAC Name 1-(2,4-dibromophenyl)-3-[(4S,5S)-2,2-dimethyl-4-phenyl-1,3-dioxan-5-yl]urea
SMILES CC1(OCC(C(O1)C2=CC=CC=C2)NC(=O)NC3=C(C=C(C=C3)Br)Br)C

Specifications

Quantity 10 mg
Formula Weight 484.18
Percent Purity >99%
Chemical Name or Material JNJ 10397049

Safety and Handling

Recommended Storage Store at +4°C
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.