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L-364,373, Tocris Bioscience™

Catalog No. 266050 Shop All R&D Systems Products
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KV7.1 channel activator, activates IKs

Activator of KV7.1 (KCNQ1) channels. Activates the cardiac IKs current that decreases action potential duration (APD) in cardiac myocytes.

Chemical Identifiers

CAS

103342-82-1

Molecular Formula

C25H20FN3O

Molecular Weight (g/mol)

397.453

InChI Key

CGBANSGENFERAT-JOCHJYFZSA-N

Synonym

r-l3, cck antagonist synthetic 11, 3r-5-2-fluorophenyl-3-1h-indol-3-ylmethyl-1-methyl-3h-1,4-benzodiazepin-2-one, d05gqk, 5-2-fluorophenyl-1,3-dihydro-3-1h-indol-3-ylmethyl-1-methyl-2h-1,4-benzodiazepin-2-one

PubChem CID

656755

ChEBI

CHEBI:34942

IUPAC Name

(3R)-5-(2-fluorophenyl)-3-(1H-indol-3-ylmethyl)-1-methyl-3H-1,4-benzodiazepin-2-one

SMILES

CN1C2=CC=CC=C2C(=NC(C1=O)CC3=CNC4=CC=CC=C43)C5=CC=CC=C5F

Specifications

Quantity

50 mg

Formula Weight

397.44

Percent Purity

>98%

Chemical Name or Material

L-364, 373

Recommended Storage

Store at +4°C
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