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  7. L-745,870 trihydrochloride, Tocris Bioscience™ 

L-745,870 trihydrochloride, Tocris Bioscience™
GSA_VA

Catalog No. p-4783577 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Highly selective D4 antagonist

A highly potent and selective D4 dopamine receptor antagonist; L-745,870 has Ki values of 0.51, 2300 and 960 nM for D4, D3 and D2 subtypes respectively and > 1000-fold selectivity over 5-HT2, D1 and D5 receptors.

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Chemical Identifiers

CAS 866021-03-6
Molecular Formula C18H22Cl4N4
Molecular Weight (g/mol) 436.202
InChI Key KJSOYZLYCFYXFC-UHFFFAOYSA-N
Synonym l-745,870 trihydrochloride, 3-4-4-chlorophenyl piperazin-1-yl methyl-1h-pyrrolo 2,3-b pyridine trihydrochloride, 3-4-4-chlorophenyl piperazin-1-yl-methyl-1h-pyrrolo 2,3-b pyridine trihydrochloride, 3-4-4-chlorophenyl piperazin-1-yl-methyl-1h-pyrrolo 2,3-b pyridine tri hydrochloride
PubChem CID 49759035
IUPAC Name 3-[[4-(4-chlorophenyl)piperazin-1-yl]methyl]-1H-pyrrolo[2,3-b]pyridine;trihydrochloride
SMILES C1CN(CCN1CC2=CNC3=C2C=CC=N3)C4=CC=C(C=C4)Cl.Cl.Cl.Cl

Specifications

Quantity 10 mg
Formula Weight 436.21
Percent Purity >99%
Chemical Name or Material L-745, 870 trihydrochloride

Safety and Handling

Recommended Storage Desiccate at +4°C
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