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L-Proline, 99%, Thermo Scientific Chemicals

Catalog No. AAA1019922
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L-Proline is used as asymmetric catalysts in organic synthesis and asymmetric aldol cyclization. It is involved in the Michael addition of dimethyl malonate to alfa-beta-unsaturated aldehydes. It is a precursor of hydroxyproline in collagen. It is an active component of collagen and involved in the proper functioning of joints and tendons. It finds uses in pharmaceutical, biotechnological applications due to its osmoprotectant property. Further, it is used with ninhydrin in the chromatography.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
L-Proline is used as asymmetric catalysts in organic synthesis and asymmetric aldol cyclization. It is involved in the Michael addition of dimethyl malonate to alfa-beta-unsaturated aldehydes. It is a precursor of hydroxyproline in collagen. It is an active component of collagen and involved in the proper functioning of joints and tendons. It finds uses in pharmaceutical, biotechnological applications due to its osmoprotectant property. Further, it is used with ninhydrin in the chromatography.

Solubility
Soluble in water and ethanol. Insoluble in ether, butanol and isopropanol.

Notes
Hygroscopic. Incompatible with strong oxidizing agents.

Chemical Identifiers

CAS

147-85-3

Molecular Formula

C5H9NO2

Molecular Weight (g/mol)

115.13

MDL Number

MFCD00064318

InChI Key

ONIBWKKTOPOVIA-UHFFFAOYNA-N

Synonym

l-proline, proline, l---proline, s-pyrrolidine-2-carboxylic acid, 2-pyrrolidinecarboxylic acid, --proline, --s-proline, 2s-pyrrolidine-2-carboxylic acid, prolinum, h-pro-oh

PubChem CID

145742

ChEBI

CHEBI:17203

IUPAC Name

(2S)-pyrrolidine-2-carboxylic acid

SMILES

OC(=O)C1CCCN1

Specifications

Melting Point

∽225°C (decomposition)

Beilstein

80810

Solubility Information

Soluble in water and ethanol. Insoluble in ether,butanol and isopropanol.

Density

1.36

Quantity

100 g

Formula Weight

115.13

Sensitivity

Hygroscopic

Chemical Name or Material

L-Proline

EINECSNumber

205-702-2

RTECSNumber

TW3584000

TSCA

Yes

Recommended Storage

Ambient temperatures

RUO – Research Use Only

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