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LE 300, Tocris Bioscience™

Catalog No. 167410 Shop All R&D Systems Products
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Quantity:
10 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Potent and selective D1 antagonist

Potent and selective dopamine D1 receptor antagonist (Ki values are 0.08 - 1.9 nM and 6 - 45 nM for D1 and D2 receptors respectively). Also displays moderate affinity for the 5-HT2A receptor (Ki = 20 nM). Active in vivo.

Chemical Identifiers

CAS 274694-98-3
Molecular Formula C20H22N2
Molecular Weight (g/mol) 290.41
InChI Key YEWGIGCYIAMFMA-UHFFFAOYSA-N
Synonym 7-methyl-6,7,8,9,14,15-hexahydro-5h-benz d indolo 2,3-g azecine, 6,7,8,9,14,15-hexahydro-7-methyl-5h-indolo 3,2-f 3 benzazecine, 11-methyl-11,21-diazatetracyclo 12.7.0.0 3 ,?.0 1 ?, 2 ? henicosa-1 14 ,3,5,7,15,17,19-heptaene, tocris-1674, le 300, solid, lopac-l-8401, d07ylk, 7-methyl-6,7,8,9,14,15-hexahydro-5h-indolo 3,2-f 3-benzazecine, 7-methyl-6,7,8,9,14,15-hexahydro-5h-indolo 3,2-f 3 benzazecine, 7-methyl-6,7,8,9,14,15-hexahydro-5h-benzo 7,8 azecino 5,4-b indole le 300
PubChem CID 4350931
SMILES CN1CCC2=CC=CC=C2CC3=C(CC1)C4=CC=CC=C4N3

Specifications

Quantity 10 mg
Formula Weight 290.41
Percent Purity >98%
Chemical Name or Material LE 300
Recommended Storage Store at Room Temperature
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