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Levcromakalim, Tocris Bioscience™

Catalog No. 137850 Shop All R&D Systems Products
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Kir6 (KATP) channel opener; active enantiomer of cromakalim (Cat. No. 1377)

Levcromakalim is an active enantiomer of the prototypical Kir6 (KATP) channel opener Cromakalim. Hypotensive and airways relaxant. IC50 = 490 nM in guinea pig trachea.

Chemical Identifiers

CAS

94535-50-9

Molecular Formula

C16H18N2O3

Molecular Weight (g/mol)

286.331

InChI Key

TVZCRIROJQEVOT-CABCVRRESA-N

Synonym

levcromakalim, lemakalim, cromakalim, --cromakalim, levcromakelim, unii-rw7pn4bldj, rw7pn4bldj, chembl100, cromakalime french, cromakalimum latin

PubChem CID

93504

ChEBI

CHEBI:6436

IUPAC Name

(3S,4R)-3-hydroxy-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)-3,4-dihydrochromene-6-carbonitrile

SMILES

CC1(C(C(C2=C(O1)C=CC(=C2)C#N)N3CCCC3=O)O)C

Specifications

Quantity

50 mg

Formula Weight

286.33

Percent Purity

>99%

Chemical Name or Material

Levcromakalim

Recommended Storage

Store at Room Temperature
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