Linezolid, 98%, Thermo Scientific Chemicals

Linezolid, Zyvox, CAS # 165800-03-3 is a synthetic oxazolidinone antibiotic.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Linezolid is an organoflourine compound and an acetamide

• Linezolid acts by inhibiting initiation complex formation by binding to the 50S ribosomal subunit

Applications

• Linezolid is effective against staphylococcal and enterococcal microbes

• It is most effective against gram-positive organisms, particularly methicillin, vancomycin and penicillin resistant ones

• Suitable for research on antibiotic resistance, cross-reactivity and drug mechanisms

Chemical Identifiers

CAS

165800-03-3

Molecular Formula

C₁₆H₂₀FN₃O₄

Molecular Weight (g/mol)

337.35

InChI Key

TYZROVQLWOKYKF-ZDUSSCGKSA-N

Synonym

linezolid, zyvox, zyvoxid, s-n-3-3-fluoro-4-morpholinophenyl-2-oxooxazolidin-5-yl methyl acetamide, zyvoxam, linezolide, linezlid, zyvoxa, linezolid usan:inn, unii-isq9i6j12j

PubChem CID

441401

ChEBI

CHEBI:63607

IUPAC Name

N-[[(5S)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide

SMILES

CC(=O)NCC1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCOCC3)F

Melting Point

181.0°C to 183.0°C

Loss on Drying

0.5% max.

Infrared Spectrum

Authentic

Assay Percent Range

97.5% min. (HPLC)

Quantity

250 mg

Solubility Information

Solubility in water: insoluble.

Formula Weight

337.35

Percent Purity

98%

Chemical Name or Material

Linezolid

Hazard Category

GHS Signal Word: Warning

Hazard Statement

GHS H Statement Causes damage to organs through prolonged or repeated exposure if inhaled.

Precautionary Statement

GHS P Statement Do not breathe dust/fume/gas/mist/vapors/spray. Get medical attention/advice if you feel unwell.

SDS

Hazard Category

GHS Signal Word: Warning

Hazard Statement

GHS H Statement Causes damage to organs through prolonged or repeated exposure if inhaled.

Precautionary Statement

GHS P Statement Do not breathe dust/fume/gas/mist/vapors/spray. Get medical attention/advice if you feel unwell.

SDS

RUO – Research Use Only