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  8. Linopirdine dihydrochloride, Tocris Bioscience™

Linopirdine dihydrochloride, Tocris Bioscience™

Catalog No. p-4784109 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

KV7 (KCNQ) channel blocker

Blocker of KV7 (KCNQ) voltage-gated potassium channels; blocks KV7.1 + 7.3 (KCNQ2 + 3)/ M-currents (IC50 = 4 - 7 μM) and KV7.1 (KCNQ1) homomeric channels (IC50 = 8.9 μM). Augments hippocampal ACh release and is a cognitive enhancer following oral administration in vivo.

Chemical Identifiers

CAS 113168-57-3
Molecular Formula C26H23Cl2N3O
Molecular Weight (g/mol) 464.39
InChI Key ZEVVHCGTTNRYOY-UHFFFAOYSA-N
Synonym linopirdine dihydrochloride, 1-phenyl-3,3-bis pyridin-4-ylmethyl indolin-2-one dihydrochloride, c26h21n3o.2hcl, 1,3-dihydro-1-phenyl-3,3-bis 4-pyridinylmethyl-2h-indol-2-one dihydrochloride, 3,3-bis 4-pyridylmethyl-1-phenylindolin-2-one dihydrochloride
PubChem CID 14209557
IUPAC Name 1-phenyl-3,3-bis(pyridin-4-ylmethyl)indol-2-one;dihydrochloride
SMILES C1=CC=C(C=C1)N2C3=CC=CC=C3C(C2=O)(CC4=CC=NC=C4)CC5=CC=NC=C5.Cl.Cl

Specifications

Quantity 10 mg
Formula Weight 464.39
Percent Purity >99%
Chemical Name or Material Linopirdine dihydrochloride

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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