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Loratadine, 98+%, Thermo Scientific Chemicals

Catalog No. AAJ60190ME
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A nonsedating-type histamine H1-receptor antagonist

Loratadine, is used as a peripheral histamine H1 receptor agonist. It is also used as an orally active antiallergic agent. It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuff.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Loratadine, is used as a peripheral histamine H1 receptor agonist. It is also used as an orally active antiallergic agent. It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuff.

Solubility
It is soluble in DMSO (50 mg/ml), ethanol (77 mg/ml at 25°C), water (<1mg/mL at 25°C), chloroform, and methanol.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C. Keep away fom strong oxidizing agents.

Chemical Identifiers

CAS

79794-75-5

Molecular Formula

C22H23ClN2O2

Molecular Weight (g/mol)

382.888

MDL Number

MFCD00672869

InChI Key

JCCNYMKQOSZNPW-UHFFFAOYSA-N

Synonym

loratadine, claritin, loratidine, alavert, clarityn, lisino, clarityne, loracert, loradex, bonalerg

PubChem CID

3957

IUPAC Name

ethyl 4-(8-chloro-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridin-11-ylidene)piperidine-1-carboxylate

SMILES

CCOC(=O)N1CCC(=C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)CC1

Specifications

Melting Point

134°C

Color

White

Quantity

500 mg

Merck Index

14,5578

Solubility Information

It is soluble in DMSO (50mg/ml),ethanol (77mg/ml at 25°C),water (<1mg/ml at 25°C),chloroform,and methanol.

Formula Weight

382.88

Percent Purity

≥98%

Physical Form

Powder

Chemical Name or Material

Loratadine

RTECSNumber

TM6129200

TSCA

No

Recommended Storage

Ambient temperatures

RUO – Research Use Only

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