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  6. LUF 5834, Tocris Bioscience™

LUF 5834, Tocris Bioscience™

Catalog No. p-4835944 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Potent adenosine A2A and A2B receptor partial agonist

LUF 5834 is a potent A2A and A2B adenosine receptor partial agonist (Ki = 2.6 nM and EC50 = 12 nM respectively). Also exhibits selectivity for A1 over A3 (Ki values are 2.6 and 538 nM respectively).

Chemical Identifiers

CAS 333962-91-7
Molecular Formula C17H12N6OS
Molecular Weight (g/mol) 348.384
InChI Key LOLJUQOCQBYBGT-UHFFFAOYSA-N
Synonym 2-1h-imidazol-2-yl methyl thio-6-amino-4-4-hydroxyphenyl pyridine-3,5-dicarbonitrile, 2-amino-4-4-hydroxyphenyl-6-1h-imidazol-2-ylmethyl thio-3,5-pyridinecarbonitrile, 2-amino-4-4-hydroxy-phenyl-6-1h-imidazol-2-ylmethylsulfanyl-pyridine-3,5-dicarbonitrile
PubChem CID 10066330
IUPAC Name 2-amino-6-(1H-imidazol-2-ylmethylsulfanyl)-4-(4-oxocyclohexa-2,5-dien-1-ylidene)-1H-pyridine-3,5-dicarbonitrile
SMILES C1=CC(=O)C=CC1=C2C(=C(NC(=C2C#N)SCC3=NC=CN3)N)C#N

Specifications

Quantity 10 mg
Formula Weight 348.38
Chemical Name or Material LUF 5834

Safety and Handling

Recommended Storage Store at -20°C
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