Thermo Scientific™ MAbPac™ SCX-10 HPLC Columns

Use these strong cation-exchange columns for high-resolution, high efficiency analysis of monoclonal antibodies (mAbs) and associated variants.

Use Thermo Scientific™ MAbPac™ SCX-10 LC Columns for high-resolution, high efficiency analysis of monoclonal antibodies (mAbs) and associated variants. The unique nonporous pellicular resin provides the resolving power to separate mAb variants that differ by as little as one charged residue. A hydrophilic layer surrounds the polymeric beads and eliminates hydrophobic interactions with the resin, resulting in very efficient peaks. A proprietary grafted cation-exchange surface provides pH selectivity control for high-resolution separations.

Superior Performance for mAb Variant Analysis

• Exceptionally high resolution for mAb variants
• Ideal for characterization and quality control assessment of mAbs
• Well-suited for stability studies, mAb therapeutic method development and high-throughput screening
•  Unmatched column-to-column and lot-to-lot reproducibility eliminates column variability as a concern in stability and QA/QC testing
• Meets the regulatory requirements for biopharmaceutical characterization

Multiple Sizes Available

• Available in 3, 5 and 10μm particle sizes in standard and UHPLC formats
• Smaller-particle-size columns provide the same resolution as the 10μm columns, but with significantly faster analysis time

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Column Format

Analytical Column

Diameter (Metric)

4 mm

Flow Rate

1 mL/min

Length (Metric)

250 mm

Max. Pressure

3000 psi (207 bar)

Particle Size

10 μm

pH

2 to 12

Pore Size

Nonporous

Solvents

50% Acetonitrile

Temperature

Ambient to 60°C

Stationary Phase

Sulfonate

Product Line

MAbPac

Packing Material

Spherical, Nonporous Polymer

Column Type

Ion Exchange

Phase

Ion Exchange

Type

Analytical Column

Technique

Bio-LC

Limited warranty period: Subject to all warranty requirements and exclusions set out in our Terms and Conditions of Sale, this product is warranted from the date we ship the product and for ninety (90) days thereafter. Disclaimer to internal research use restriction: Any restrictions on the purchaser to utilize the product(s) for internal research purposes only does not apply to the product(s) on the web pages associated with this statement.