Thermo Scientific Chemicals Melatonine, 99%

Melatonine, 99%, CAS # 73-31-4, is a hormone usually produced in the pineal gland and released into the blood.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Melatonine is a hormone produced by the pineal gland that shows several biological activities, including the somnolence, sleep-wake cycle, circadian rhythm, stress response, aging, and immunity activities

• It shows antioxidant, autocoid, paracoid, hormonal, anti- inflammatory and anti-apoptotic activities

Applications

• Melatonin shows neurohormonal activity and can upregulate antioxidant enzymes and inhibit rat NOS1

• Melatonin has been reported to be an activator of MEL-1A-R and MEL-1B-R

• The production and secretion of melatonine are dependent on beta-adrenergic receptor function

• During melatonine synthesis, the essential amino acid L-tryptophan is used as a precursor

• This compound inhibits apoptosis in immune cells and neurons, and enhances apoptotic cell death of cancer cells

• It can inhibit proliferation and metastasis of breast cancer cells by modulating Rho-associated kinase protein-1 expression

Chemical Identifiers

CAS

73-31-4

Molecular Formula

C₁₃H₁₆N₂O₂

Molecular Weight (g/mol)

232.28

MDL Number

MFCD00005655

InChI Key

DRLFMBDRBRZALE-UHFFFAOYSA-N

Synonym

melatonin, melatonine, n-acetyl-5-methoxytryptamine, circadin, 5-methoxy-n-acetyltryptamine, n-2-5-methoxy-1h-indol-3-yl ethyl acetamide, melatol, melatonex, melovine

PubChem CID

896

ChEBI

CHEBI:16796

IUPAC Name

N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide

SMILES

CC(=O)NCCC1=CNC2=C1C=C(C=C2)OC

Melting Point

116.0°C to 120.0°C

Color

White or Cream to Yellow

Loss on Drying

0.5% max. (1 g, 105°C)

Infrared Spectrum

Authentic

Assay Percent Range

98.5% min. (HPLC)

Packaging

Glass bottle

Quantity

5 g

Beilstein

22, V,12, 42

Merck Index

15, 5884

Solubility Information

Solubility in water: insoluble. Other solubilities: soluble in ethanol,benzene,toluene,hexane,acet,onitrile

Formula Weight

232.28

Percent Purity

99%

Physical Form

Powder

Chemical Name or Material

Melatonine

EINECSNumber

200-797-7

SDS

EINECSNumber

200-797-7

SDS

RUO – Research Use Only