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Methyl-beta-cyclodextrin, Thermo Scientific Chemicals

Catalog No. AAJ6684706
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Cavity size is the major determinant as to which cyclodextrin is used in complexation. The cavity diameter of β-cyclodextrins or β-glucopyranose unit compounds is well-suited for use with molecules the size of hormones, vitamins and many compounds frequently used in tissue and cell culture applications. For this reason, β-cyclodextrin is most commonly used as a complexing agent. It is used to increase the solubility of non-polar substances such as fatty acids, lipids, vitamins and cholesterol for use in cell culture applications. Methyl-β-cyclodextrin is used to remove cholesterol from cultured cells and is employed to remove lipid rafts.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Cavity size is the major determinant as to which cyclodextrin is used in complexation. The cavity diameter of β-cyclodextrins or β-glucopyranose unit compounds is well-suited for use with molecules the size of hormones, vitamins and many compounds frequently used in tissue and cell culture applications. For this reason, β-cyclodextrin is most commonly used as a complexing agent. It is used to increase the solubility of non-polar substances such as fatty acids, lipids, vitamins and cholesterol for use in cell culture applications. Methyl-β-cyclodextrin is used to remove cholesterol from cultured cells and is employed to remove lipid rafts.

Solubility
Soluble in water

Notes
Store at room temperature. Incompatible with heat, oxidizing agents.

Chemical Identifiers

CAS

128446-36-6

Molecular Formula

C54H94O35

Molecular Weight (g/mol)

1303.311

MDL Number

MFCD00074980

InChI Key

YZOUYRAONFXZSI-SBHWVFSVSA-N

Synonym

beta-cyclodextrin methyl ethers, beta-cyd, methyl-?cyclodextrin, beta-w7 m1.8, dimethyl-, a-cyclodextrin, .beta.-cyclodextrin,methylethers, methyl-b-cyclodextrin cell culture*tested

PubChem CID

51051622

SMILES

COC1C(C2C(OC1OC3C(OC(C(C3OC)OC)OC4C(OC(C(C4OC)OC)OC5C(OC(C(C5OC)OC)OC6C(OC(C(C6OC)OC)OC7C(OC(C(C7OC)OC)OC8C(OC(O2)C(C8O)OC)CO)CO)CO)CO)CO)CO)CO)O

Specifications

Melting Point

180°C to 182°C

Color

White

Quantity

5 g

Solubility Information

Soluble in water

Physical Form

Powder

Chemical Name or Material

Methyl-beta-cyclodextrin

Hazard Category

H317-H361

Precautionary Statement

P201-P202-P261-P272-P280g-P281-P302+P352-P308+P313-P333+P313-P363-P501c

EINECSNumber

411-120-1

TSCA

Yes

Recommended Storage

Ambient temperatures

RUO – Research Use Only

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