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  6. Methyl-beta-cyclodextrin, Thermo Scientific Chemicals

Methyl-beta-cyclodextrin, Thermo Scientific Chemicals

Catalog No. p-7057555
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Quantity:
5 g
25 g

Description

Cavity size is the major determinant as to which cyclodextrin is used in complexation. The cavity diameter of β-cyclodextrins or β-glucopyranose unit compounds is well-suited for use with molecules the size of hormones, vitamins and many compounds frequently used in tissue and cell culture applications. For this reason, β-cyclodextrin is most commonly used as a complexing agent. It is used to increase the solubility of non-polar substances such as fatty acids, lipids, vitamins and cholesterol for use in cell culture applications. Methyl-β-cyclodextrin is used to remove cholesterol from cultured cells and is employed to remove lipid rafts.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Cavity size is the major determinant as to which cyclodextrin is used in complexation. The cavity diameter of β-cyclodextrins or β-glucopyranose unit compounds is well-suited for use with molecules the size of hormones, vitamins and many compounds frequently used in tissue and cell culture applications. For this reason, β-cyclodextrin is most commonly used as a complexing agent. It is used to increase the solubility of non-polar substances such as fatty acids, lipids, vitamins and cholesterol for use in cell culture applications. Methyl-β-cyclodextrin is used to remove cholesterol from cultured cells and is employed to remove lipid rafts.

Solubility
Soluble in water

Notes
Store at room temperature. Incompatible with heat, oxidizing agents.

Chemical Identifiers

CAS 128446-36-6
Molecular Formula C54H94O35
Molecular Weight (g/mol) 1303.311
MDL Number MFCD00074980
InChI Key YZOUYRAONFXZSI-SBHWVFSVSA-N
Synonym beta-cyclodextrin methyl ethers, beta-cyd, methyl-?cyclodextrin, beta-w7 m1.8, dimethyl-, a-cyclodextrin, .beta.-cyclodextrin,methylethers, methyl-b-cyclodextrin cell culture*tested
PubChem CID 51051622
SMILES COC1C(C2C(OC1OC3C(OC(C(C3OC)OC)OC4C(OC(C(C4OC)OC)OC5C(OC(C(C5OC)OC)OC6C(OC(C(C6OC)OC)OC7C(OC(C(C7OC)OC)OC8C(OC(O2)C(C8O)OC)CO)CO)CO)CO)CO)CO)CO)O

Specifications

Melting Point 180°C to 182°C
Color White
Quantity 5 g
Solubility Information Soluble in water
Physical Form Powder
Chemical Name or Material Methyl-beta-cyclodextrin

Safety and Handling

Hazard Category H317-H361
Precautionary Statement P201-P202-P261-P272-P280g-P281-P302+P352-P308+P313-P333+P313-P363-P501c
EINECSNumber 411-120-1
TSCA Yes
Recommended Storage Ambient temperatures
SDS

RUO – Research Use Only

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