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Metyrapone, Tocris Bioscience™

Catalog No. 329250 Shop All R&D Systems Products
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Quantity:
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

11-β hydroxylase inhibitor

Cytochrome P450 inhibitor. Blocks glucocorticoid synthesis via inhibition of steroid 11-β hydroxylase (CYP11B1) activity (IC50 = 7.83 μM). Also inhibits CYP3A4 and cytochrome P450-mediated ω/ω-1 hydroxylase activity.

Chemical Identifiers

CAS 54-36-4
Molecular Formula C14H14N2O
Molecular Weight (g/mol) 226.28
MDL Number MFCD00006397
InChI Key FJLBFSROUSIWMA-UHFFFAOYSA-N
Synonym metyrapone, metopirone, 2-methyl-1,2-di-3-pyridyl-1-propanone, methopyrapone, metopiron, methapyrapone, methopirapone, methopyrinine, methopyrone, metyrapon
PubChem CID 4174
ChEBI CHEBI:44241
IUPAC Name 2-methyl-1,2-bis(pyridin-3-yl)propan-1-one
SMILES CC(C)(C(=O)C1=CC=CN=C1)C1=CC=CN=C1

Specifications

Quantity 50 mg
Formula Weight 226.27
Percent Purity >99%
Chemical Name or Material Metyrapone

Safety and Handling

Recommended Storage Store at +4°C
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