MitoPY1, Tocris Bioscience™

Description

Fluorescent mitochondrial hydrogen peroxide indicator

Fluorescent probe for imaging hydrogen peroxide (H2O2) in mitochondria of living cells. Displays enhanced emission at 528 nm in the presence of H2O2. Selective for H2O2 over superoxide, nitric oxide and hydroxyl radical. Detects local increases in H2O2 in an in vitro model of Parkinson's Disease.

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Specifications

Chemical Identifiers

• CAS: 1041634-69-8
• Molecular Formula: C52H53BIN2O5P
• Molecular Weight (g/mol): 954.693
• InChI Key: JPCCULDYUUMFAD-UHFFFAOYSA-M
• Synonym: mitopy1, 4-4-3-oxo-6'-4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl spiro isobenzofuran-1 3h ,9'-9h xanthen-3'-yl-1-piperazinyl butyl triphenyl-phosphonium iodide
• PubChem CID: 90488942
• IUPAC Name: 4-[4-[3-oxo-6'-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)spiro[2-benzofuran-1,9'-xanthene]-3'-yl]piperazin-1-yl]butyl-triphenylphosphanium;iodide
• SMILES: B1(OC(C(O1)(C)C)(C)C)C2=CC3=C(C=C2)C4(C5=C(O3)C=C(C=C5)N6CCN(CC6)CCCC[P+](C7=CC=CC=C7)(C8=CC=CC=C8)C9=CC=CC=C9)C1=CC=CC=C1C(=O)O4.[I-]

• Quantity: 10 mg
• Formula Weight: 954.68
• Percent Purity: >98%
• Chemical Name or Material: MitoPY1

Safety and Handling

Recommended Storage

Store at -20°C