Invitrogen™ Mouse C/EBP alpha (aa 1-14) Synthetic Peptide

Synthetic Peptide

Mouse CEBP alpha (residues 1-14) Synthetic Peptide, PEP-242, from Invitrogen.

The C/EBP (CCAAT/enhancer binding protein) family of transcription factors--alpha, beta, delta, and epsilon)--are widely expressed proteins found in a variety of tissues. These domains contain an evolutionarily conserved five-amino acid motif (the regulatory domain motif RDM) that conforms to the consensus sequence (I/V/L) KXEP. One of the major roles of these transcription factors is that of metabolic regulation in liver and fat cells. Studies suggest that these transcription factors act in a cascade aiding in the development of the adipose cell. Three C/EBP beta isoforms (LAP*, LAP, and LIP) arise from different translation initiation and display different function in gene regulation. From a neurological standpoint, C/EBPs have been implicated in the mediation of nerve growth factor, altering synaptic plasticity, and mediation of inflammatory response in AD patients. PEP-242 is a 14 amino acid synthetic peptide corresponding to amino acid residues 1-14 from mouse C/EBP alpha. The sequence of this peptide is (amino to carboxy terminus): M E S A D F Y E V E P R P P.This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product, catalog &Num; MA1-825. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (∽70-fold) for competitive inhibition of antibody-protein binding reactions.Reconstitute with 0.1 mL of distilled water.

Gene ID (Entrez)

12606

Species

Mouse

Purification Method

purified

Accession Number

P53566

Common Name

Mouse C/EBP alpha (aa 1-14)

Concentration

0.5 mg/mL

Content And Storage

-20°C. Avoid freeze-thaw cycles.

Description

Synthetic Peptide

Format

Lyophilized

Formulation

peptide with no preservative

For Use With (Application)

Control

Gene Symbol

Cebpa

Lyophilized

Yes

Preservative

No preservative

Product Type

Peptide

Quantity

50 μg

Regulatory Status

RUO - research use only

Sequence

M E S A D F Y E V E P R P P