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ACROBiosystems FITC-Labeled Monoclonal Anti-FMC63 scFv Antibody, Mouse IgG1 is expressed from human HEK293 cells. It is the FITC labeled form of Monoclonal Anti-FMC63 scFv Antibody, Mouse IgG1 (Cat. No. FM3-Y45P1).
Supplier: ACROBiosystems FM3FY45P1200TESTS
FMC63 is an IgG2a mouse monoclonal antibody specific for CD19, which is a target for the immunotherapy of B lineage leukaemias and lymphomas. FMC63 scFv is the most commonly used ectodomain component of CD19-specific CARs. So far, most of reported CART19 trials contain the anti-CD19 scFv derived from FMC63, including the two FDA-approved CARs Kymriah and Yescarta.
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