MP Biomedicals™ Concanavalin A from Canavalia ensiformis seeds

Description

Metalloprotein that requires transition metal ion, such as manganese and calcium ions for binding

Con A is a relatively weak blood agglutinin. More than 10μg/mL may be required to give visible agglutination of neuraminidase treated human erythrocytes.

• CAS Number: 11028-71-0
• EC Number: 234-258-2
• MDL Number: MFCD00071069
• Format: Highly purified, essentially salt free, powder
• Extinction Coefficient (1%): 280nm=11.4 (0.1M NaCl)
• Isoelectric point (pI): 4.5, 4.7, 5.0 to 5.1 and 5.4 to 5.5 (several isoforms)
• Soluble in water

Used for in vitro applications including blood grouping and erythrocyte polyagglutination studies, mitogenic stimulation of lymphocytes, lymphocyte subpopulation studies, fractionation of cells and other particles, histochemical studies of normal and pathological conditions. Con-A has been used to elucidate structural changes in the membrane surface of transformed cells. Con-A conjugates of antitumor drugs have been used in drug delivery systems in cultured cells.

Specifications

• Formulation: 0.05M Tris, 0.15M NaCl, 0.004M CaCl2, pH 7
• Name: Jack Bean Concanavalin A
• pH Range: 7
• Quantity: 1 g
• Source: Jack Bean
• Storage Requirements: 0°C
• Cross Reactivity: Jack Bean
• Form: Powder