MPP dihydrochloride, Tocris Bioscience™

Description

Highly selective ERα antagonist

Selective, high affinity silent antagonist at ERα receptors. Displays > 200-fold selectivity for ERα over ERβ. Ki values are 2.7 and 1800 nM at ERα and ERβ receptors respectively.

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Specifications

Chemical Identifiers

• CAS: 911295-24-4
• Molecular Formula: C29H33Cl2N3O3
• Molecular Weight (g/mol): 542.501
• InChI Key: SMPRQALBFACGGO-UHFFFAOYSA-N
• Synonym: mpp dihydrochloride, 1,3-bis-4-hydroxyphenyl-4-methyl-5-4-2-piperidinylethoxy phenol-1h-pyrazole dihydrochloride, mpp dihydrochloride hydrate, methyl-piperidino-pyrazole hydrate, 1,3-bis 4-hydroxyphenyl-4-methyl-5-4-2-piperidinylethoxy phenol-1h-pyrazole dihydrochloride, mpp dihydrochloride hydrate hplc , white powder, 1,3-bis 4-hydroxyphenyl-4-methyl-5-4-2-piperidinylethoxy phenol-1h-pyrazole dihydrochloride hydrate, 4-1-4-hydroxyphenyl-4-methyl-5-4-2-piperidin-1-yl ethoxy phenyl-1,2-dihydro-3h-pyrazol-3-ylidene cyclohexa-2,5-dien-1-one-hydrogen chloride 1/2, 4-3-4-hydroxyphenyl-4-methyl-5-4-2-piperidin-1-yl ethoxy phenyl pyrazol-1-yl phenol dihydrochloride
• PubChem CID: 45073474
• IUPAC Name: 4-[2-(4-hydroxyphenyl)-4-methyl-3-[4-(2-piperidin-1-ylethoxy)phenyl]-1H-pyrazol-5-ylidene]cyclohexa-2,5-dien-1-one;dihydrochloride
• SMILES: CC1=C(N(NC1=C2C=CC(=O)C=C2)C3=CC=C(C=C3)O)C4=CC=C(C=C4)OCCN5CCCCC5.Cl.Cl

• Quantity: 10 mg
• Formula Weight: 542.5
• Percent Purity: >98%
• Chemical Name or Material: MPP dihydrochloride

Safety and Handling

Recommended Storage

Desiccate at +4°C