Learn More
N,N'-Dicyclohexylcarbodiimide, 99%, Thermo Scientific Chemicals
N,N'-Dicyclohexylcarbodiimide is a carboxyl activating reagent used in peptide synthesis. It acts as a dehydrating agent for the preparation of amides, ketones and nitriles. It is involved in the preparation of esters by reacting tertiary alcohols with carboxylic acid. It is utilized for the stereo chemical inversion of secondary alcohols by forming formyl ester followed by saponification. It is associated with dimethyl sulfoxide and used in Pfitzner-Moffatt oxidation to convert alcohols into aldehydes and ketones.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
N,N′-Dicyclohexylcarbodiimide is a carboxyl activating reagent used in peptide synthesis. It acts as a dehydrating agent for the preparation of amides, ketones and nitriles. It is involved in the preparation of esters by reacting tertiary alcohols with carboxylic acid. It is utilized for the stereo chemical inversion of secondary alcohols by forming formyl ester followed by saponification. It is associated with dimethyl sulfoxide and used in Pfitzner-Moffatt oxidation to convert alcohols into aldehydes and ketones.
Solubility
Soluble in methanol, chloroform, dichloromethane, acetonitrile, tetrahydrofuran and dimethylformamide. Insoluble in water.
Notes
Incompatible with strong oxidizing agents.
Specifications
Melting Point
33°C to 36°C
Boiling Point
154°C to 156°C (11 mmHg)
Flash Point
138°C (280°F)
Quantity
100 g
UN Number
UN2811
Beilstein
610662
Sensitivity
Moisture sensitive
Merck Index
14,3096
Solubility Information
Soluble in methanol,chloroform,dichloromethane,acetonitrile,tetrahydrofuran and dimethylformamide. Insoluble in water.
Formula Weight
206.33
Hazard Category
H302-H311-H317-H318
Hazard Statement
GHS H Statement
H311-H318-H302-H317
Toxic in contact with skin.
Causes serious eye damage.
Harmful if swallowed.
May cause an allergic skin reaction.
Precautionary Statement
P261-P264b-P270-P272-P280-P301+P312-P302+P352-P305+P351+P338-P310-P312-P330-P333+P313-P361-P363-P501c
DOTInformation
Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
EINECSNumber
208-704-1
RTECSNumber
FF2160000
TSCA
Yes
Recommended Storage
Ambient temperatures; Store under Nitrogen
RUO – Research Use Only
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.