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N,N'-Disuccinimidyl carbonate, tech. 85%, remainder N-Hydroxysuccinimide, Thermo Scientific Chemicals

Catalog No. AAH2662914
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N,N'-Disuccinimidyl carbonate is used to prepare cleavable linker succinimide vinylsufonylethyl carbonate for thiol modified-DNA. It serves as a reagent for the synthesis of carbamates. Further, it is used as a coupling reagent as well as in the preparation of N-succinimidyl esters of N-protected amino acids, activated carbonate and coupling of ligand to proteins.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N,N′-Disuccinimidyl carbonate is used to prepare cleavable linker succinimide vinylsufonylethyl carbonate for thiol modified-DNA. It serves as a reagent for the synthesis of carbamates. Further, it is used as a coupling reagent as well as in the preparation of N-succinimidyl esters of N-protected amino acids, activated carbonate and coupling of ligand to proteins.

Solubility
Soluble in dimethyl sulfoxide, hot pyridine, acetonitrile and most organic solvents. Insoluble in water.

Notes
Moisture sensitive. Store in a cool place. Incompatible with strong acids and oxidizing agents.

Chemical Identifiers

CAS

74124-79-1

Molecular Formula

C9H8N2O7

Molecular Weight (g/mol)

256.17

MDL Number

MFCD00009767

InChI Key

PFYXSUNOLOJMDX-UHFFFAOYSA-N

Synonym

n,n'-disuccinimidyl carbonate, bis 2,5-dioxopyrrolidin-1-yl carbonate, n,n'-disuccinimidylcarbonate, di succinimido carbonate, disuccinimidyl carbonate, di n-succinimidyl carbonate, n,n-disuccinimidyl carbonate, dsc, disuccinimido carbonate, pubchem12700

PubChem CID

676246

IUPAC Name

bis(2,5-dioxopyrrolidin-1-yl) carbonate

SMILES

C1CC(=O)N(C1=O)OC(=O)ON2C(=O)CCC2=O

Specifications

Melting Point

190°C (decomposition)

Quantity

25 g

Beilstein

1499137

Sensitivity

Hygroscopic

Solubility Information

Soluble in dimethyl sulfoxide,hot pyridine,acetonitrile and most organic solvents. Insoluble in water.

Formula Weight

256.17

Percent Purity

85%

Grade

Technical

Assay

remainder N-Hydroxysuccinimide

Chemical Name or Material

N,N'-Disuccinimidyl carbonate

Hazard Category

H315-H319-H335

Hazard Statement

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

Precautionary Statement

P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c

EINECSNumber

277-730-3

TSCA

No

Recommended Storage

Keep cold; Store under Nitrogen
SDS

RUO – Research Use Only

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