N-Succinimidyl 3-maleimidobenzoate, 95%, Thermo Scientific Chemicals

A heterobifunctional coupling reagent useful for forming enzyme immunoconjugates

N-Succinimidyl 3-maleimidobenzoate is useful for forming enzyme immunoconjugates. It has a 9.9 Angstrom spacer arm. Heterobifunctional crosslinking reagent reactive toward primary amine and sulfhydryl. Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N-Succinimidyl 3-maleimidobenzoate is useful for forming enzyme immunoconjugates. It has a 9.9 Angstrom spacer arm. Heterobifunctional crosslinking reagent reactive toward primary amine and sulfhydryl. Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates

Solubility
Soluble in DMF or ethyl acetate.

Notes
Moisture & Light Sensitive. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Chemical Identifiers

CAS

58626-38-3

Molecular Formula

C15H10N2O6

Molecular Weight (g/mol)

314.253

MDL Number

MFCD00005514

InChI Key

LLXVXPPXELIDGQ-UHFFFAOYSA-N

Synonym

3-maleimidobenzoic acid n-hydroxysuccinimide ester, n-succinimidyl 3-maleimidobenzoate, 3-maleimidobenzoyl n-hydroxysuccinimide, 1-3-2,5-dioxopyrrolidinyl oxy carbonyl phenyl-1h-pyrrole-2,5-dione, m-maleimidobenzoyl-n-hydroxysuccinimide ester, 2,5-dioxopyrrolidin-1-yl 3-2,5-dioxopyrrol-1-yl benzoate, 3-n-maleimidobenzoic acid n-succinimidyl ester, 2,5-dioxopyrrolidin-1-yl 3-2,5-dioxo-2,5-dihydro-1h-pyrrol-1-yl benzoate, ambotzpeg2090

PubChem CID

93861

IUPAC Name

(2,5-dioxopyrrolidin-1-yl) 3-(2,5-dioxopyrrol-1-yl)benzoate

SMILES

C1CC(=O)N(C1=O)OC(=O)C2=CC(=CC=C2)N3C(=O)C=CC3=O

Melting Point

175°C to 177°C

Color

White

Quantity

250 mg

Beilstein

1505254

Sensitivity

Light and moisture sensitive

Solubility Information

Soluble in DMF or ethyl acetate.

Formula Weight

314.26

Percent Purity

95%

Physical Form

Powder

Chemical Name or Material

N-Succinimidyl 3-maleimidobenzoate

Hazard Category

H315-H319-H335

Hazard Statement

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

Precautionary Statement

P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c

EINECSNumber

261-368-8

TSCA

No

Recommended Storage

Store at -20°C

SDS

Hazard Category

H315-H319-H335

Hazard Statement

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

Precautionary Statement

P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c

EINECSNumber

261-368-8

TSCA

No

Recommended Storage

Store at -20°C

SDS

RUO – Research Use Only