β-Nicotinamide Adenine Dinucleotide, MP Biomedicals™

Acts as a major electron acceptor molecule in biological oxidations. β-Nicotinamide Adenine Dinucleotide, MP Biomedicals serves as a coenzyme of the dehydrogenases and acts as a hydrogen acceptor. β-NAD is one of the biologically active forms of

β-NAD occurs in living cells primarily in the oxidized state.

• Serves as a coenzyme of hydride-transfer enzymes in dehydrogenases, especially in the dehydrogenation of primary and secondary alcohols
• Usually acts as a hydrogen acceptor, forming NADH, which then serves as a hydrogen donor in the respiratory chain
• Used as a substrate for NAD(+)-consuming enzymes, which include ADP-ribose transferases, poly(ADP-ribose) polymerases, cADP-ribose synthases and sirtuins
• Recently reported to be a P2Y11 agonist

Chemical Identifiers

CAS

53-84-9

Molecular Formula

C21H26N7O14P2-

Molecular Weight (g/mol)

662.422

InChI Key

BAWFJGJZGIEFAR-NNYOXOHSSA-M

Synonym

nicotinamide adenine dinucleotide, nad+, diphosphopyridine nucleotide, nad-oxidized, nicotinamide-adenine dinucleotide, dpn-ox, beta-nicotinamide adenine dinucleotide, dpn+, nad, nad +

PubChem CID

15938971

ChEBI

CHEBI:57540

IUPAC Name

[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] [(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate

SMILES

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OCC3C(C(C(O3)N4C=NC5=C4N=CN=C5N)O)O)O)O)C(=O)N

Absorbance

λ max (water): 259 ± 3nm

Melting Point

160°C (literature)

pH

2 to 4 (1% aq. soln.)

Quantity

500 mg

Solubility Information

Soluble in water (200mg/mL)

Formula Weight

663.4 (anhydrous)

Percent Purity

≥98%

Physical Form

Powder

Recommended Storage

0°C, desiccate

Recommended Storage

0°C, desiccate