Nicotinoyl chloride hydrochloride, 96%, Thermo Scientific Chemicals

Description

Nicotinoyl chloride hydrochloride was used in the preparation of 1-[5-O-tert-butyldimethylsilyl-2-deoxy-2-fluoro-3-O-(3-pyridylcarbonyl)-β-D-ribofuranosyl]uracil, bis(ethylenedithio)tetrathiafulvalene derivatives and 7,16-dinicotinoylated or 7,16-diisonicotinoylated compounds via reaction with tetraaza[14]annulene and its complexes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Nicotinoyl chloride hydrochloride was used in the preparation of 1-[5-O-tert-butyldimethylsilyl-2-deoxy-2-fluoro-3-O-(3-pyridylcarbonyl)-β-D-ribofuranosyl]uracil, bis(ethylenedithio)tetrathiafulvalene derivatives and 7,16-dinicotinoylated or 7,16-diisonicotinoylated compounds via reaction with tetraaza[14]annulene and its complexes.

Solubility
It decomposes in water.

Notes
Moisture sensitive. Incompatible with oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 20260-53-1
• Molecular Formula: C6H5Cl2NO
• Molecular Weight (g/mol): 178.012
• MDL Number: MFCD00012820
• InChI Key: MSYBLBLAMDYKKZ-UHFFFAOYSA-N
• Synonym: nicotinoyl chloride hydrochloride, pyridine-3-carbonyl chloride hydrochloride, nicotinoyl chloride, hydrochloride, 3-pyridinecarbonyl chloride, hydrochloride, 3-pyridinecarbonyl chloride hydrochloride, nicotinic acid chloride hydrochloride, nicotinoylchloride hydrochloride, 3-pyridinecarbonyl chloride, hydrochloride 1:1, nicotinyl chloride hydrochloride, nicotinoyl chloride hcl
• PubChem CID: 88438
• IUPAC Name: pyridine-3-carbonyl chloride;hydrochloride
• SMILES: C1=CC(=CN=C1)C(=O)Cl.Cl

• Melting Point: 149°C to 155°C
• Quantity: 10 g
• UN Number: UN3261
• Beilstein: 3655772
• Sensitivity: Moisture sensitive
• Solubility Information: It decomposes in water.
• Formula Weight: 178.02
• Percent Purity: 98%
• Chemical Name or Material: Nicotinoyl chloride hydrochloride

Safety and Handling

Hazard Category	H314
Hazard Statement	GHS H Statement H314-H318 Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statement	P260-P264b-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c
DOTInformation	Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S.
EINECSNumber	243-648-1
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only