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NS 1619, Tocris Bioscience™

Catalog No. 380410 Shop All R&D Systems Products
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Activator of BKCa (KCa1.1) channels

Large-conductance Ca2+-activated potassium (BKCa, KCa1.1) channel activator. Induces a concentration-dependent decrease in mitochondrial membrane potential (EC50 = 3.6 μM).

Chemical Identifiers

CAS

153587-01-0

Molecular Formula

C15H8F6N2O2

Molecular Weight (g/mol)

362.231

InChI Key

YLFMCMWKHSDUCT-UHFFFAOYSA-N

Synonym

1-2-hydroxy-5-trifluoromethyl phenyl-5-trifluoromethyl-1h-benzo d imidazol-2 3h-one, 1,3-dihydro-1-2-hydroxy-5-trifluoromethyl phenyl-5-trifluoromethyl-2h-benzimidazol-2-one, 1-2'-hydroxy-5'-trifluoromethylphenyl-5-trifluoromethyl-2 3h-benzimidazolone, 1-2-hydroxy-5-trifluoromethyl phenyl-5-trifluoromethyl-1,3-dihydro-2h-benzimidazol-2-one, 3-2-hydroxy-5-trifluoromethyl phenyl-6-trifluoromethyl-1h-benzimidazol-2-one, 2h-benzimidazol-2-one,1,3-dihydro-1-2-hydroxy-5-trifluoromethyl phenyl-5-trifluoromethyl, 1-2-hydroxy-5-trifluoromethyl phenyl-5-trifluoromethyl-3h-1,3-benzodiazol-2-one, acmc-20agb2, ns 1619, powder, lopac-n-170

PubChem CID

4552

ChEBI

CHEBI:34879

IUPAC Name

3-[2-hydroxy-5-(trifluoromethyl)phenyl]-6-(trifluoromethyl)-1H-benzimidazol-2-one

SMILES

C1=CC2=C(C=C1C(F)(F)F)NC(=O)N2C3=C(C=CC(=C3)C(F)(F)F)O

Specifications

Quantity

10 mg

Formula Weight

362.23

Percent Purity

>98%

Chemical Name or Material

NS 1619

Recommended Storage

Store at +4°C
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