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NS 1643, Tocris Bioscience™

Catalog No. 306250 Shop All R&D Systems Products
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KV11.1 (hERG) channel activator; antiarrhythmic

Human ether-a-go-go related gene (hERG) KV11.1 channel activator (EC50 = 10.5 μM). Exhibits different molecular mechanisms of action at KV11.1 (hERG1) and KV11.2 (hERG2) channels. Displays antiarrhythmic activity in vitro.

Chemical Identifiers

CAS

448895-37-2

Molecular Formula

C15H10F6N2O3

Molecular Weight (g/mol)

380.246

InChI Key

NJFVQMRYJZHGME-UHFFFAOYSA-N

Synonym

1,3-bis 2-hydroxy-5-trifluoromethyl phenyl urea, unii-0i579cng0i, n,n'-bis 2-hydroxy-5-trifluoromethyl phenyl urea, urea, n,n'-bis 2-hydroxy-5-trifluoromethyl phenyl, 1,3-bis 2-hydroxy-5-trifluoromethylphenyl urea, ns hplc , solid

PubChem CID

10177784

IUPAC Name

1,3-bis[2-hydroxy-5-(trifluoromethyl)phenyl]urea

SMILES

C1=CC(=C(C=C1C(F)(F)F)NC(=O)NC2=C(C=CC(=C2)C(F)(F)F)O)O

Specifications

Quantity

50 mg

Formula Weight

380.24

Percent Purity

>98%

Chemical Name or Material

NS 1643

Recommended Storage

Store at +4°C
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