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NS 1738, Tocris Bioscience™

Catalog No. 299550 Shop All R&D Systems Products
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Positive allosteric modulator of α7 nAChR; active in vivo

Selective positive allosteric modulator of α7 nicotinic acetylcholine receptors. Exhibits no substantial activity for α4β2, α3β3 and α1-containing receptors. Displays cognitive-enhancing properties in vivo.

Chemical Identifiers

CAS

501684-93-1

Molecular Formula

C14H9Cl2F3N2O2

Molecular Weight (g/mol)

365.133

InChI Key

OUDXRNQPVSMGDW-UHFFFAOYSA-N

Synonym

n-5-chloro-2-hydroxyphenyl-n'-2-chloro-5-trifluoromethyl phenyl urea, 1-5-chloro-2-hydroxyphenyl-3-2-chloro-5-trifluoromethyl phenyl urea, d0d4lf, urea, n-5-chloro-2-hydroxyphenyl-n'-2-chloro-5-trifluoromethyl phenyl, 1-5-chloro-2-hydroxy-phenyl-3-2-chloro-5-trifluoromethyl-phenyl-urea, 3-5-chloro-2-hydroxyphenyl-1-2-chloro-5-trifluoromethyl phenyl urea, n-3-chloro-6-hydroxy-phenyl-n'-2-chloro-5-trifluoromethyl-phenyl urea

PubChem CID

310378

IUPAC Name

1-(5-chloro-2-hydroxyphenyl)-3-[2-chloro-5-(trifluoromethyl)phenyl]urea

SMILES

C1=CC(=C(C=C1C(F)(F)F)NC(=O)NC2=C(C=CC(=C2)Cl)O)Cl

Specifications

Quantity

50 mg

Formula Weight

365.13

Percent Purity

98%

Chemical Name or Material

NS 1738

Recommended Storage

Store at Room Temperature
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