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  5. Tocris Bioscience™ NS 19504

Tocris Bioscience™ NS 19504

Catalog No. p-7110799 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

KCa1.1 (BK) channel activator

NS 19504 is a selective activator of large-conductance Ca2+-activated potassium channels (BKCa, KCa1.1) (EC50 = 11 μM). Activates BK channels in native smooth muscle cells from guinea pig bladder and reduces spontaneous phasic contractions in bladder strips ex vivo. Displays no effect on contractions induced by a high K+ concentration or at 65 other receptors tested, including L- and N- type Ca2+ channels, Nav, KATP and hERG channels.

Specifications

Chemical Name or Material 5-[(4-Bromophenyl)methyl]-2-thiazolamine
CAS 327062-46-4
Quantity 10 mg
Target Ca2+-Activated Potassium Channel Activators
Molecular Formula C10H9BrN2S
Formula Weight 269.16
Purity >99%
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