Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

p-Toluenesulfonylmethyl isocyanide, 97%, Thermo Scientific Chemicals

Catalog No. AAA1431222
Click to view available options
Quantity:

p-Toluenesulfonylmethyl isocyanide is a synthetic reagent used in the synthesis of triplet drugs with the 1,3,5-trioxazatriquinane skeleton, pyrroles, oxazoles and in imidazoles. It serves as an isonitrile component in a diastereoselective Passerini reaction. Furthermore, it is used in the Van Leusen reaction to convert aldehydes to nitriles.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
p-Toluenesulfonylmethyl isocyanide is a synthetic reagent used in the synthesis of triplet drugs with the 1,3,5-trioxazatriquinane skeleton, pyrroles, oxazoles and in imidazoles. It serves as an isonitrile component in a diastereoselective Passerini reaction. Furthermore, it is used in the Van Leusen reaction to convert aldehydes to nitriles.

Solubility
Soluble in chloroform and methanol. Insoluble in water.

Notes
Moisture, air and light sensitive. Store in cool place. Incompatible with strong bases and strong oxidizing agents.

Chemical Identifiers

CAS

36635-61-7

Molecular Formula

C9H9NO2S

Molecular Weight (g/mol)

195.24

MDL Number

MFCD00000005

InChI Key

CFOAUYCPAUGDFF-UHFFFAOYSA-N

Synonym

tosylmethyl isocyanide, tosmic, p-toluenesulfonylmethyl isocyanide, 4-toluenesulphonylmethyl isocyanide, 4-toluenesulfonylmethyl isocyanide, tosylmethylisocyanide, 1-isocyanomethylsulfonyl-4-methylbenzene, p-tolylsulfonyl methyl isocyanide, unii-c35fd6olh8, 1-isocyanomethyl sulfonyl-4-methylbenzene

PubChem CID

161915

IUPAC Name

1-(isocyanomethylsulfonyl)-4-methylbenzene

SMILES

CC1=CC=C(C=C1)S(=O)(=O)C[N+]#[C-]

Specifications

Melting Point

109°C to 114°C

Quantity

100 g

UN Number

UN2811

Beilstein

3592382

Sensitivity

Moisture sensitive

Solubility Information

Soluble in chloroform and methanol. Insoluble in water.

Formula Weight

195.24

Percent Purity

≥97%

Chemical Name or Material

p-Toluenesulfonylmethyl isocyanide

Hazard Category

H301+H311+H331-H334

Hazard Statement

GHS H Statement
H300-H311-H331
Fatal if swallowed.
Toxic in contact with skin.
Toxic if inhaled.

Precautionary Statement

P261-P264b-P270-P271-P280-P285-P301+P310-P302+P352-P304+P340-P311-P312-P330-P361-P363-P501c

DOTInformation

Transport Hazard Class: 6.1; Packing Group: II; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.

EINECSNumber

253-140-1

TSCA

No

Recommended Storage

Ambient temperatures; Store under Nitrogen
SDS

RUO – Research Use Only

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.