AdipoGen Paeoniflorin

Supplier:  AdipoGen CDXP0260M100

Chemical. CAS 23180-57-6. Formula C23H28O11. MW 480.46. Paeoniflorin has diverse cellular actions, including modulating NMDA and TRPV1 receptors. It is reported to inhibit testosterone synthesis and stimulate aromatase activity. It also reduces inflammatory signaling by inhibiting p38 MAP kinase and blocks pancreatic cancer cell apoptosis by suppressing MMP-2/9 and ERK signaling. It has been described as an adenosine A1 receptor activator with neuroprotective and antidepressant effects, as well as hypoglycemic activity. It can activate adenosine A-1 receptors to increase the translocations of PKC and GLUT4, two major signals for glucose uptake, from cytosol to membrane of the white adipocytes in rats. Recently it also was described as a liver X receptor LXR agonist, that can act as a ligand-activated transcription factor to exhibit antihyperlipidemic and neuroprotective effects.

Catalog No. 50-256-0197