Paxilline, 97+%, Thermo Scientific Chemicals

Description

Potent blocker of high-conductance calcium-activated potassium (BKCa) channels

Potent blocker of high-conductance calcium-activated potassium (BKCa) channels

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Specifications

Chemical Identifiers

• CAS: 57186-25-1
• Molecular Formula: C27H33NO4
• Molecular Weight (g/mol): 435.564
• MDL Number: MFCD00083464
• InChI Key: ACNHBCIZLNNLRS-UBGQALKQSA-N
• Synonym: paxilline, unii-3t9u9z96l7, 2h-1-benzopyrano 5',6':6,7 indeno 1,2-b indol-3 4bh-one, 5,6,6a,7,12,12b,12c,13,14,14a-decahydro-4b-hydroxy-2-1-hydroxy-1-methylethyl-12b,12c-dimethyl-, 2-alpha,4b-beta,6a-alpha,12b-beta,12c-alpha,14a-beta, 2h-pyrano 2,3:5',6' benz 1',2':6,7 indeno 1,2-b indol-3 4bh-one, 5,6,6a,7,12,12b,12c,13,14,14a-decahydro-4b-hydroxy-2-1-hydroxy-1-methylethyl-12b,12c-dimethyl-, 2r,4bs,6as,12bs,12cr,14as, spectrum5_001975, paxilline, powder hplc, paxilline solution, 100 mug/ml in acetonitrile, analytical standard, 2r,4bs,6as,12bs,12cr,14as-5,6,6a,7,12,12b,12c,13,14,14a-decahydro-4b-hydroxy-2-1-hydroxy-1-methylethyl-12b,12c-dimethyl-2h-pyrano 2,3:5',6' benz 1',2':6,7 indeno 1,2-b indol-3 4bh-one, ncgc00025342-07_c27h33no4_ 2r,4bs,6as,12bs,12cr,14as-4b-hydroxy-2-2-hydroxy-2-propanyl-12b,12c-dimethyl-5,6,6a,7,12,12b,12c,13,14,14a-decahydro-2h-chromeno 5',6':6,7 indeno 1,2-b indol-3 4bh-one
• PubChem CID: 105008
• ChEBI: CHEBI:34907
• SMILES: CC12CCC3C(=CC(=O)C(O3)C(C)(C)O)C1(CCC4C2(C5=C(C4)C6=CC=CC=C6N5)C)O

• Color: White to Yellow
• Quantity: 5 mg
• UN Number: UN2811
• Solubility Information: Soluble in DMSO,acetone or chloroform.
• Formula Weight: 435.56
• Percent Purity: ≥97%
• Physical Form: Powder
• Chemical Name or Material: Paxilline

Safety and Handling

Hazard Category	H301+H311-H315-H318-H330-H335
Hazard Statement	GHS H Statement H300-H310-H330-H318-H315-H335 Fatal if swallowed. Fatal in contact with skin. Fatal if inhaled. Causes serious eye damage. Causes skin irritation. May cause respiratory irritation.
Precautionary Statement	P260-P264b-P270-P271-P280-P284-P301+P310-P302+P352-P304+P340-P305+P351+P338-P310-P312-P330-P332+P313-P361-P363-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: II; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
RTECSNumber	DJ2830000
TSCA	No
Recommended Storage	Store at -20°C

SDS

RUO – Research Use Only