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PCI 34051, Tocris Bioscience™

Catalog No. p-4835954 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent and selective HDAC8 inhibitor

Potent and selective histone deacetylase 8 (HDAC8) inhibitor (IC50 = 10 nM). Displays >200 fold selectivity over HDAC isoforms 1, 2, 3, 6 and 10. Induces apoptosis in cell lines derived from T cell lymphomas or leukemias.

Chemical Identifiers

CAS 950762-95-5
Molecular Formula C17H16N2O3
Molecular Weight (g/mol) 296.326
InChI Key AJRGHIGYPXNABY-UHFFFAOYSA-N
Synonym unii-pui52vxv61, n-hydroxy-1-4-methoxybenzyl-1h-indole-6-carboxamide, pui52vxv61, n-hydroxy-1-4-methoxyphenyl methyl indole-6-carboxamide, n-hydroxy-1-4-methoxyphenyl methyl-1h-indole-6-carboxamide, d0q5mc, 1h-indole-6-carboxamide, n-hydroxy-1-4-methoxyphenyl methyl, hdac 8 inhibitors cancer/inflammation, 1-4-methoxybenzyl-n-hydroxy-1h-indole-6-carboxamide, 1-4-methoxyphenyl methyl indole-6-carbohydroxamic acid
PubChem CID 24753719
IUPAC Name N-hydroxy-1-[(4-methoxyphenyl)methyl]indole-6-carboxamide
SMILES COC1=CC=C(C=C1)CN2C=CC3=C2C=C(C=C3)C(=O)NO

Specifications

Quantity 10 mg
Formula Weight 296.32
Chemical Name or Material PCI 34051

Safety and Handling

Recommended Storage Store at -20°C
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