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PD 150606, Tocris Bioscience™

Catalog No. 126950 Shop All R&D Systems Products
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Cell permeable calpain inhibitor

Selective, cell-permeable non-peptide calpain inhibitor (Ki values for ν and m-calpains are 0.21 and 0.37 μM respectively). Targets the calcium binding sites of calpain. Demonstrates high specificity for calpains relative to other proteases, and is a non-competitive inhibitor with respect to the substrate.

Chemical Identifiers

CAS

179528-45-1

Molecular Formula

C9H7IO2S

Molecular Weight (g/mol)

306.117

InChI Key

DJCVSFWGKYHMKH-YVMONPNESA-N

Synonym

3-4-iodophenyl-2-mercapto-z-2-propenoic acid, 2z-3-4-iodophenyl-2-sulfanylprop-2-enoic acid, 4'-iodo-2-mercaptocinnamic acid, z-3-4-iodophenyl-2-mercaptoacrylic acid, pd hplc, z-3-4-iodophenyl-2-mercapto-2-propenoic acid, 2z-3-4-iodophenyl-2-mercapto-2-propenoic acid, z-3-4-iodophenyl-2-sulfanyl-prop-2-enoic acid

PubChem CID

9839500

IUPAC Name

(Z)-3-(4-iodophenyl)-2-sulfanylprop-2-enoic acid

SMILES

C1=CC(=CC=C1C=C(C(=O)O)S)I

Specifications

Quantity

50 mg

Formula Weight

306.12

Percent Purity

>95%

Chemical Name or Material

PD 150606

Recommended Storage

Store at -20°C
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