Gibco™ PeproGMP® Human Flt-3 Ligand (FLT3L) Recombinant Protein, PeproTech®

Recombinant Protein

FLT3LG (Fms Related Tyrosine Kinase 3 Ligand) is a Protein Coding gene. Diseases associated with FLT3LG include Aplastic Anemia and Brain Cancer. Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Ras signaling pathway. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and cytokine activity. Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8-positive classical DCs and their CD103-positive tissue counterparts.

Accession Number

P49771

For Use With (Application)

Functional Assay

Format

Lyophilized

Formulation

Protein with no preservative

Molecular Weight (g/mol)

17.6

Name

FLT3LG

Quantity

100 μg

Immunogen

Human Flt-3 Ligand (FLT3L)

Storage Requirements

-20°C or -80°C if preferred

Regulatory Status

RUO

Endotoxin Concentration

<0.1

Assays

Functional Assay

Conjugate

Unconjugated

Recombinant

Recombinant

Activity

Determined by its ability to stimulate human AML5 cell proliferation. PeproGMP Recombinant Human Flt3-Ligand has been tested against the WHO standard NIBSC 96/532.

Expression System

E. coli

Product Line

PeproGMP

Purity or Quality Grade

Purified