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Phenyl chloroformate, 99%, Thermo Scientific Chemicals
Phenyl chloroformate is used in the synthesis of poly(2-(phenoxycarbonyloxy)ethyl methacrylate) and phenyl-(4-vinylphenyl) carbonate. It acts as a precursor of phenyl mixed anhydrides which are used in peptide coupling reactions. It serves as a dehydrating reagent for the conversion of primary amides to nitriles and an intermediate in the synthesis of pharmaceuticals and carbamates.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Phenyl chloroformate is used in the synthesis of poly(2-(phenoxycarbonyloxy)ethyl methacrylate) and phenyl-(4-vinylphenyl) carbonate. It acts as a precursor of phenyl mixed anhydrides which are used in peptide coupling reactions. It serves as a dehydrating reagent for the conversion of primary amides to nitriles and an intermediate in the synthesis of pharmaceuticals and carbamates.
Solubility
Miscible with N,N-dimethylformamide.
Notes
Store in cool place. Moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with bases, alcohols and amines. Hydrolyses in water.
Specifications
Melting Point
-38°C
Density
1.246
Boiling Point
188°C to 189°C
Flash Point
76°C (169°F)
Refractive Index
1.511
Quantity
100 g
UN Number
UN2746
Beilstein
606778
Sensitivity
Moisture sensitive
Solubility Information
Miscible with N,N-dimethylformamide.
Hazard Category
H227-H302-H314-H317-H330-H335
Hazard Statement
GHS H Statement
H330-H314-H318-H227-H302-H317
Fatal if inhaled.
Causes severe skin burns and eye damage.
Causes serious eye damage.
Combustible liquid.
Harmful if swallowed.
May cause an allergic skin reaction.
Precautionary Statement
P210-P235-P260-P264b-P270-P271-P272-P280-P284-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P333+P313-P363-P370+P378q-P501c
DOTInformation
Transport Hazard Class: 6.1; Packing Group: II; Proper Shipping Name: PHENYL CHLOROFORMATE
EINECSNumber
217-547-8
RTECSNumber
FG3850000
TSCA
Yes
Recommended Storage
Keep cold; Store under Nitrogen
RUO – Research Use Only
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