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  8. PHTPP, Tocris Bioscience™

PHTPP, Tocris Bioscience™

Catalog No. p-4784291 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Selective ERβ antagonist

Selective estrogen ERβ receptor antagonist that displays 36-fold selectivity over ERα. Exhibits full antagonism at ERβ in a cotransfection assay in human endometrial cancer cells (HEC-1), with minimal effects on ERα.

Chemical Identifiers

CAS 805239-56-9
Molecular Formula C20H11F6N3O
Molecular Weight (g/mol) 423.318
InChI Key AEZPAUSGTAHLOQ-UHFFFAOYSA-N
Synonym phtpp, 4-2-phenyl-5,7-bis trifluoromethyl pyrazolo 1,5-a pyrimidin-3-yl phenol, d02wru, pyrazolo 1,5-a pyrimidine, 2a, phtpp hplc
PubChem CID 11201035
IUPAC Name 4-[2-phenyl-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]phenol
SMILES C1=CC=C(C=C1)C2=NN3C(=CC(=NC3=C2C4=CC=C(C=C4)O)C(F)(F)F)C(F)(F)F

Specifications

Quantity 10 mg
Formula Weight 423.31
Percent Purity >99%
Chemical Name or Material PHTPP

Safety and Handling

Recommended Storage Store at Room Temperature
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