Thermo Scientific™ DMS (dimethyl suberimidate)

Description

Crosslink amines to amines with dimethyl suberimidate (CAS 34490-86-3); composed of imidoester groups at either end of a membrane-permeable, 8-atom spacer arm.

Thermo Scientific™ Pierce DMS is dimethyl suberimidate, a membrane-permeable crosslinker that contains an amine-reactive imidoester group at each end of an 8-atom spacer arm.

Highlights:

• Water-soluble
• Rapid reaction with amines at alkaline pH values (pH 8-10)
• Amidine bond retains net charge character of protein
• Reversible at high pH values
• Reactive groups: imidoester (homobifunctional)
• Reactive toward: amino groups

Specifications

• Chemical Reactivity: Amine-Amine
• Cleavable: No
• Description: DMS
• Molecular Weight (g/mol): 273.2
• PEGylated: No
• Spacer Arm Length: 11.0 Å
• Content And Storage: Upon receipt store desiccated at 4°C.
• Cell Permeability: Yes
• Shipping Condition: Ambient
• Product Line: Pierce™
• Labeling Method: Chemical Labeling
• Crosslinker Type: Homobifunctional
• Reactive Moiety: Imidoester
• Spacer: Medium (10 to 30 Å)
• Form: Powder
• Quantity: 1 g
• Solubility: Water
• Format: Standard
• Water Soluble: Yes
• Product Type: Crosslinker

For Research Use Only. Not for use in diagnostic procedures.