Thermo Scientific™ Pierce™ DSP, No-Weigh™ Format

Crosslink amines to amines with dithiobis succinimidyl propionate, composed of NHS-ester groups and disulfide-containing, 12.0A spacer arm and cleavable with reducing agents.

Thermo Scientific™ Pierce DSP Crosslinker (Lomant's Reagent) is an amine-reactive crosslinker with NHS-ester reactive ends and a cleavable disulfide bond in its spacer arm.

Highlights:

• Cleavable by reducing agents
• Membrane-permeable
• Acylate in aqueous or organic media within two minutes at room temperature
• Four- to five-hour half-life of ester at pH 7.0
• Reactive groups: NHS ester (homobifunctional)
• Reactive toward: amino groups

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Chemical Reactivity

Amine-Amine

Cleavable

By Thiols

Description

DSP

Molecular Weight (g/mol)

404.42

PEGylated

No

Spacer Arm Length

12.0 Å

Content And Storage

Upon receipt store desiccated at 4°C.

Cell Permeability

Yes

Shipping Condition

Ambient

Product Line

Pierce™

Labeling Method

Chemical Labeling

Crosslinker Type

Homobifunctional

Reactive Moiety

NHS Ester

Spacer

Medium (10 to 30 Å)

Form

Powder

Quantity

1 g

Solubility

DMF, DMSO

Format

Standard, Single-use, Premium-grade

Water Soluble

No

Product Type

Crosslinker

For Research Use Only. Not for use in diagnostic procedures.