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  6. PI22349

Thermo Scientific™ SIA (succinimidyl iodoacetate)

Catalog No. PI22349 Shop All Thermo Scientific Products
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Reactive groups: NHS ester and iodoacetyl

Description

Crosslink amines to sulfhydryls with this very short crosslinker composed of NHS-ester and iodoacetyl (haloacetyl) groups at ends of a 3-atom (1.5A) spacer arm.

Thermo Scientific™ Pierce SIA is a very short (1.5 Å) crosslinker for amine-to-sulfhydryl conjugation via N-hydroxysuccinimide (NHS) ester and iodoacetyl reactive groups.

Suited to capturing amine and sulfhydryl groups in very close proximity

Highlights:

  • Reactive groups: NHS ester and iodoacetyl
  • Reactive toward: amino and sulfhydryl groups

Specifications

Chemical Reactivity Amine-Sulfhydryl
Cleavable No
Description SIA
Molecular Weight (g/mol) 283.02
PEGylated No
Spacer Arm Length 1.5 Å
Content And Storage Upon receipt store at 4°C protected from moisture.
Cell Permeability Yes
Shipping Condition Ambient
Product Line Pierce™
Labeling Method Chemical Labeling
Crosslinker Type Heterobifunctional
Reactive Moiety Haloacetyl, NHS Ester
Spacer Short (<10 Å)
Form Solid
Quantity 50 mg
Solubility DMF, DMSO
Format Standard
Water Soluble No
Product Type Crosslinker
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For Research Use Only. Not for use in diagnostic procedures.

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