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Pitavastatin calcium, Tocris Bioscience™

Catalog No. p-4817307 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

HMG-CoA reductase inhibitor

Synthetic inhibitor of HMG-CoA reductase (Ki = 1.7 nM). Lowers low-density lipoprotein (LDL) cholesterol levels. Displays minimal metabolism by cytochrome P450 enzymes, with little involvement of CYP3A4. Shown to improve cardiac function and survival in a rat model of hypertensive heart failure.

Chemical Identifiers

CAS 147526-32-7
Molecular Formula C50H46CaF2N2O8
Molecular Weight (g/mol) 881.00
MDL Number MFCD01937979
InChI Key RHGYHLPFVJEAOC-FFNUKLMVSA-L
Synonym pitavastatin calcium
PubChem CID 131673901
IUPAC Name calcium bis((3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoate)
SMILES [Ca++].O[C@H](C[C@H](O)\C=C\C1=C(N=C2C=CC=CC2=C1C1=CC=C(F)C=C1)C1CC1)CC([O-])=O.O[C@H](C[C@H](O)\C=C\C1=C(N=C2C=CC=CC2=C1C1=CC=C(F)C=C1)C1CC1)CC([O-])=O

Specifications

Quantity 10 mg
Formula Weight 440.5
Percent Purity >99%
Chemical Name or Material Pitavastatin calcium

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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