PNU 142633, Tocris Bioscience™

Description

Highly selective 5-HT1D agonist

Very selective, high affinity 5-HT1D receptor agonist (Ki values are 6 and > 18000 nM at human 5-HT1D and 5-HT1B receptors respectively). Inhibits sympathetically-induced tachycardic responses and blocks neurogenic plasma protein extravasation in vivo.

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Specifications

Chemical Identifiers

• CAS: 187665-65-2
• Molecular Formula: C24H30N4O3
• Molecular Weight (g/mol): 422.529
• InChI Key: PNTVCCRNJOGKGA-QFIPXVFZSA-N
• Synonym: unii-b54p1bq73l, d03swh, 1s-1-2-4-4-aminocarbonyl phenyl-1-piperazinyl ethyl-3,4-dihydro-n-methyl-1h-2-benzopyran-6-carboxamide, 1h-2-benzopyran-6-carboxamide, 1-2-4-4-aminocarbonyl phenyl-1-piperazinyl ethyl-3,4-dihydro-n-methyl-, 1s, 1s-1-2-4-4-carbamoylphenyl piperazin-1-yl ethyl-n-methyl-3,4-dihydro-1h-2-benzopyran-6-carboxamide, s-1-2-4-4-carbamoyl-phenyl-piperazin-1-yl-ethyl-isochroman-6-carboxylic acid methylamide
• PubChem CID: 9845148
• IUPAC Name: (1S)-1-[2-[4-(4-carbamoylphenyl)piperazin-1-yl]ethyl]-N-methyl-3,4-dihydro-1H-isochromene-6-carboxamide
• SMILES: CNC(=O)C1=CC2=C(C=C1)C(OCC2)CCN3CCN(CC3)C4=CC=C(C=C4)C(=O)N

• Quantity: 10 mg
• Formula Weight: 422.53
• Percent Purity: >98%
• Chemical Name or Material: PNU 142633

Safety and Handling

Recommended Storage

Store at +4°C