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  7. PNU 37883 hydrochloride, Tocris Bioscience™

PNU 37883 hydrochloride, Tocris Bioscience™

Catalog No. p-4784323 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Vascular Kir6 (KATP) channel blocker

Novel antagonist selective for the vascular form of Kir6 (KATP) channel; inhibits Kir6 currents in isolated mesenteric artery smooth muscle cells (Kd = 65 nM) but not in cardiac or skeletal myocytes. Inhibits blood vessel relaxation and hypotension induced by pinacidil in vivo. Displays weak diuretic effects.

Chemical Identifiers

CAS 57568-80-6
Molecular Formula C21H36ClN3O
Molecular Weight (g/mol) 381.989
InChI Key FZALCKUJYZCDOX-UHFFFAOYSA-N
Synonym pnu 37883 hydrochloride, 4-morpholinecarboximidine-n-1-adamantyl-n'-cyclohexane, n-cyclohexyl-n'-tricyclo 3.3.1.1 3,7 dec-1-yl-4-morpholinecarboximidamide monohydrochloride, 4-morpholinecarboximidamide, n-cyclohexyl-n'-tricyclo 3.3.1.1 3,7 dec-1-yl-, monohydrochloride, c21h35n3o.hcl, n-1-adamantyl-n'-cyclohexylmorpholine-4-carboximidamide hydrochloride, n-cyclohexyl-n'-tricyclo 3.3.1.13,7 dec-1-yl-4-morpholinecarboximidamide hydrochloride, n-1-adamantyl-n inverted exclamation marka-cyclohexyl-4-morpholinecarboxamidine hydrochloride
PubChem CID 64392
IUPAC Name N-(1-adamantyl)-N'-cyclohexylmorpholine-4-carboximidamide;hydrochloride
SMILES C1CCC(CC1)N=C(NC23CC4CC(C2)CC(C4)C3)N5CCOCC5.Cl

Specifications

Quantity 10 mg
Formula Weight 381.98
Percent Purity >99%
Chemical Name or Material PNU 37883 hydrochloride

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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