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PQ 401, Tocris Bioscience™

Catalog No. 276850 Shop All R&D Systems Products
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IGF1R inhibitor

Insulin-like growth factor receptor (IGF1R) inhibitor. Suppresses IGF-stimulated IGF-IR autophosphorylation with an IC50 value of 12 μM. Inhibits growth of MCF-7 breast cancer cells in vitro and in vivo.

Chemical Identifiers

CAS

196868-63-0

Molecular Formula

C18H16ClN3O2

Molecular Weight (g/mol)

341.80

MDL Number

MFCD00160558

InChI Key

YBLWOZUPHDKFOT-UHFFFAOYSA-N

Synonym

igf-1r inhibitor ii, 1-5-chloro-2-methoxyphenyl-3-2-methylquinolin-4-yl urea, unii-2n3lv83s8j, n-5-chloro-2-methoxyphenyl-n'-2-methyl-4-quinolinyl urea, n-2-methoxy-5-chlorophenyl-n′-2-methylquinolin-4-yl-urea, d0b4su, urea, n-5-chloro-2-methoxyphenyl-n'-2-methyl-4-quinolinyl, pq hplc , powder, 3-5-chloro-2-methoxyphenyl-1-2-methylquinolin-4-yl urea, n-2-methoxy-5-chlorophenyl-n'-2-methylquinolin-4-yl-urea

PubChem CID

9549305

IUPAC Name

1-(5-chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea

SMILES

COC1=C(NC(=O)NC2=C3C=CC=CC3=NC(C)=C2)C=C(Cl)C=C1

Specifications

Quantity

50 mg

Formula Weight

341.79

Percent Purity

>99%

Chemical Name or Material

PQ 401

Recommended Storage

Store at +4°C
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