CEACAM Pan Mouse anti-Human, Clone: TET2, Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific VDQ2

Catalog No. 01-670-173

Description

This antibody recognizes native human CEACAM1, 5, 6, 8 protein expressed in transfected mammalian cells.

CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family. The CEA family proteins belong to the immuno-globulin (Ig) superfamily and are composed of one Ig variable-like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains. CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells or in leucocytes. Over-expression of CEA/CEACAM5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker. The function of CEACAM family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria.

Specifications

• Antigen: CEACAM Pan
• Classification: Monoclonal
• Concentration: 2 mg/mL
• Gene: CEACAM1
• Gene Alias: pan CEACAM, Carcinoembryonic antigen-related cell adhesion molecule 1, BGP, BGP-1, CD66a, Biliary glycoprotein 1, Carcinoembryonic antigen-related cell adhesion molecule 5, CEA, CD66e, Carcinoembryonic antigen-related cell adhesion molecule 6, CD66c, NCA, Carcinoembryonic antigen-related cell adhesion molecule 8, CD67, Carcinoembryonic antigen CGM6, CGM6, CD66b
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 1048, 1088, 4680, 634
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Western Blot
• Clone: TET2
• Conjugate: Unconjugated
• Gene Accession No.: P06731, P13688, P31997, P40199
• Gene Symbols: CEACAM1, CEACAM5, CEACAM6, CEACAM8
• Immunogen: extracted protein of CEACAM5
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b