R&D Systems™ Recombinant Human CD38 Fc Chimera Protein, CF

Recombinant Protein

Measured by its ability to convert the substrate nicotinamide guanine dinucleotide (NGD+) to cyclic GDP-ribose. Graeff, R.M. et al. (1994) J. Biol. Chem. 269:30260. The specific activity is >900 pmol/min/μg, as measured under the described conditions.

Accession Number

P28907.2

For Use With (Application)

Enzyme Activity

Formulation

Supplied as a 0.2 μm filtered solution in MES and NaCl.

Gene ID (Entrez)

952

Molecular Weight (g/mol)

M.W.-observed: 67-74 kDa, under reducing conditions, M.W.-theroretical: 57 kDa

Quantity

20 μg

Source

Human embryonic kidney cell, HEK293-derived human CD38 protein Human CD38 (Val43-Ile300) (N-terminus) Accession # P28907.2 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)

Storage Requirements

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20°C to -70°C as supplied. 3 months, -20°C to -70°C under sterile conditions after opening.

Endotoxin Concentration

<0.10 EU / 1 μg of the protein by the LAL method.

Gene Alias

2 '-phospho-ADP-ribosyl cyclase, 2 '-phospho-ADP-ribosyl cyclase/2 '-phospho-cyclic-ADP-ribose transferase (EC:2.4.99.20), 2 '-phospho-cyclic-ADP-ribose transferase, ADPRC 1, ADPRC1, ADP-ribosyl Cyclase, ADP-ribosyl cyclase 1, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, cADPr hydrolase 1, CD_antigen: CD38, CD38, CD38 antigen, CD38 antigen (p45), CD38 molecule, cluster of differentiation 38, Cyclic ADP-ribose Hydrolase, Cyclic ADP-ribose hydrolase 1, EC 2.4.99.20, EC 3.2.2.6, EC:3.2.2.6, NAD(+) nucleosidase, T10

Conjugate

Unconjugated

Purity or Quality Grade

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.

Protein

CD38