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R&D Systems™ Recombinant Mouse TGF-beta RI/ALK-5 Fc Chimera Protein

Catalog No. 587RIB050 Shop All R&D Systems Products
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This item is not returnable. View return policy

Carrier Free Recombinant Protein

Measured by its binding ability in a functional ELISA. When Recombinant Mouse Endoglin/CD105 Fc Chimera Protein (Catalog # 1320-EN ) is immobilized at 2.00μg/mL (100μL/well), Recombinant Mouse TGF-beta RI/ALK-5 Fc Chimera (Catalog # 587-RIB) binds with an ED50 of 2.00-15.0μg/mL.

Specifications

Accession Number

BAA05023.1

For Use With (Application)

Bioactivity

Formulation

Supplied as a 0.2μm filtered solution in PBS.

Gene ID (Entrez)

7046

Molecular Weight (g/mol)

M.W. (Observed): 40-50 kDa, under reducing conditions., M.W. (Theoretical): 37.5 kDa (monomer)

Quantity

50 μg

Source

Spodoptera frugiperda, Sf 21 (baculovirus)-derived mouse TGF-beta RI/ALK-5 protein Mouse TGF-beta RI (Ala21-Glu121) & (Thr22-Glu121) (N-terminus) Accession # BAA05023.1 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)

Storage Requirements

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after opening. 3 months, -20 to -70 °C under sterile conditions after opening.

Endotoxin Concentration

<0.10 EU per 1μg of the protein by the LAL method.

Gene Alias

AAT5, activin A receptor type II-like kinase, 53kD, activin A receptor type II-like kinase, 53kDa, Activin receptor-like kinase 5, ACVRLK4, ALK-5, ALK-5ALK5, EC 2.7.11, EC 2.7.11.30, LDS1A, LDS2A, Serine/threonine-protein kinase receptor R4, SKR4, TbetaR-I, TGFB1R1, TGF-beta receptor type I, TGF-beta receptor type-1, TGF-beta type I receptor, TGFbetaRI, TGFBR1, TGF-bRI, TGFR-1, transforming growth factor beta receptor I, transforming growth factor, beta receptor 1, transforming growth factor, beta receptor I (activin A receptor type II-likekinase, 53kD), Transforming growth factor-beta receptor type I

Conjugate

Unconjugated

Species

Mouse

Purity or Quality Grade

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.

Protein

TGF-beta RI/ALK-5

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